Detalhe da pesquisa
1.
Tracking Cancer Evolution Reveals Constrained Routes to Metastases: TRACERx Renal.
Cell
; 173(3): 581-594.e12, 2018 04 19.
Artigo
Inglês
| MEDLINE | ID: mdl-29656895
2.
Tumor-associated macrophages expressing the transcription factor IRF8 promote T cell exhaustion in cancer.
Immunity
; 55(11): 2044-2058.e5, 2022 11 08.
Artigo
Inglês
| MEDLINE | ID: mdl-36288724
3.
TGF-ß suppresses type 2 immunity to cancer.
Nature
; 587(7832): 115-120, 2020 11.
Artigo
Inglês
| MEDLINE | ID: mdl-33087928
4.
Nivolumab plus Cabozantinib versus Sunitinib for Advanced Renal-Cell Carcinoma.
N Engl J Med
; 384(9): 829-841, 2021 03 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33657295
5.
Lenvatinib plus pembrolizumab in patients with either treatment-naive or previously treated metastatic renal cell carcinoma (Study 111/KEYNOTE-146): a phase 1b/2 study.
Lancet Oncol
; 22(7): 946-958, 2021 07.
Artigo
Inglês
| MEDLINE | ID: mdl-34143969
6.
Overcome tumor heterogeneity-imposed therapeutic barriers through convergent genomic biomarker discovery: A braided cancer river model of kidney cancer.
Semin Cell Dev Biol
; 64: 98-106, 2017 04.
Artigo
Inglês
| MEDLINE | ID: mdl-27615548
7.
SETD2 alterations impair DNA damage recognition and lead to resistance to chemotherapy in leukemia.
Blood
; 130(24): 2631-2641, 2017 12 14.
Artigo
Inglês
| MEDLINE | ID: mdl-29018079
8.
Genomic classifications of renal cell carcinoma: a critical step towards the future application of personalized kidney cancer care with pan-omics precision.
J Pathol
; 244(5): 525-537, 2018 04.
Artigo
Inglês
| MEDLINE | ID: mdl-29266437
9.
Genomically annotated risk model for advanced renal-cell carcinoma: a retrospective cohort study.
Lancet Oncol
; 19(12): 1688-1698, 2018 12.
Artigo
Inglês
| MEDLINE | ID: mdl-30416077
10.
In Vivo PET Assay of Tumor Glutamine Flux and Metabolism: In-Human Trial of 18F-(2S,4R)-4-Fluoroglutamine.
Radiology
; 287(2): 667-675, 2018 05.
Artigo
Inglês
| MEDLINE | ID: mdl-29388903
11.
Molecular Subtypes Improve Prognostic Value of International Metastatic Renal Cell Carcinoma Database Consortium Prognostic Model.
Oncologist
; 22(3): 286-292, 2017 03.
Artigo
Inglês
| MEDLINE | ID: mdl-28220024
12.
Deadly splicing: Bax becomes Almighty.
Mol Cell
; 33(2): 145-6, 2009 Jan 30.
Artigo
Inglês
| MEDLINE | ID: mdl-19187757
13.
Stepwise activation of BAX and BAK by tBID, BIM, and PUMA initiates mitochondrial apoptosis.
Mol Cell
; 36(3): 487-99, 2009 Nov 13.
Artigo
Inglês
| MEDLINE | ID: mdl-19917256
14.
Validation and genomic interrogation of the MET variant rs11762213 as a predictor of adverse outcomes in clear cell renal cell carcinoma.
Cancer
; 122(3): 402-10, 2016 Feb 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26505625
15.
Circulating biomarkers and outcome from a randomised phase II trial of sunitinib vs everolimus for patients with metastatic renal cell carcinoma.
Br J Cancer
; 114(6): 642-9, 2016 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26908330
16.
A Phase Ib Study of BEZ235, a Dual Inhibitor of Phosphatidylinositol 3-Kinase (PI3K) and Mammalian Target of Rapamycin (mTOR), in Patients With Advanced Renal Cell Carcinoma.
Oncologist
; 21(7): 787-8, 2016 07.
Artigo
Inglês
| MEDLINE | ID: mdl-27286790
17.
Phosphorylation of MLL by ATR is required for execution of mammalian S-phase checkpoint.
Nature
; 467(7313): 343-6, 2010 Sep 16.
Artigo
Inglês
| MEDLINE | ID: mdl-20818375
18.
TCEB1-mutated renal cell carcinoma: a distinct genomic and morphological subtype.
Mod Pathol
; 28(6): 845-853, 2015 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-25676555
19.
Radiogenomics of clear cell renal cell carcinoma: associations between CT imaging features and mutations.
Radiology
; 270(2): 464-71, 2014 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-24029645
20.
Impact of recurrent copy number alterations and cancer gene mutations on the predictive accuracy of prognostic models in clear cell renal cell carcinoma.
J Urol
; 192(1): 24-9, 2014 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-24518768